Oscar Darío Citeli (Caja de Compensación familiar de Nariño). Teonila Castro Generalidades del cáncer gástrico en Colombia. el riesgo de desarrollar Cáncer gástrico: Tumaco-Nariño, bajo riesgo; gástricas como: gastritis crónica, úlcera péptica, Cáncer gástrico y linfoma tipo MALT. Alvaro Pazos Universidad de Nariño; Luis Eduardo Bravo Univalle; Andrés Betancourt Palabras clave: Gastritis crónica; microbiota láctica; cáncer gástrico ;.

Author: Grokinos Malaramar
Country: Burma
Language: English (Spanish)
Genre: Technology
Published (Last): 10 September 2015
Pages: 63
PDF File Size: 1.29 Mb
ePub File Size: 8.69 Mb
ISBN: 319-7-93647-189-6
Downloads: 54210
Price: Free* [*Free Regsitration Required]
Uploader: Tygoll

Gonzalez CA, Agudo A. Gastric cancer is one of the most common malignant diseases with one of the highest mortality rates worldwide. Eventually, foci of dysplasia may arise in metaplastic epithelium; these foci are usually small and therefore the diagnosis narko subject to sampling error. Another possible factor is differences in the content of salt NaCl in the diet of people living in the mountains versus those living in the coast, since salt has been associated with gastric cancer risk in many countries [ 36 ].

Material used came from 7 biopsies of the gastric mucosa taken from each patient using Olympus Actera video endoscopy. Previously, it was left to the judgment of the physicians involved to classify the tumors located at the esophagogastric junction as esophageal or gastric.

In Colombia, stomach cancer also ranks fourth in incidence after prostate, breast, and cervical cancers and second in mortality after prostate cancer 3. Curr Issues Intest Microbiol. This immune response is not effective in eliminating the bacterium gastrioc may last years to decades, causing chronic active gastritis, unless the infection is eradicated.

N Engl J Med. The staging of gastritis with the OLGA system by using intestinal metaplasia as an accurate alternative for atrophic gastritis. Notable exceptions exist, as outlined below. Two 2 biopsies were taken from the antrum fve centimeters from the pylorus; one 1 from the angular incision, two 2 from the corpus ten centimeters from the cardia and two 2 from the subcardia.

Male patients were twice as nxrio to have EBV-positive tumors as female patients, and tumors arising in the gastric cardia or corpus were more than twice as likely to be EBV-positive as those in the antrum. Management of precancerous conditions and lesions in the stomach MAPS: Gastritis is a very frequent pathological entity in the Andes Region which is treated by general practitioners, surgeons, internists and gastroenterologists in Colombia.


The intestinal type adenocarcinoma is thought to gasrico from the precancerous lesions previously described. Incomplete metaplasia consists of goblet cells alternating with columnar mucous cells containing varying amounts of intracytoplasmic mucin. While evidence of the regression of metaplasia after treatment to eradicate this infection has been demonstrated, controversy remains with regard to this subject. A similar contrast in gastric cancer incidence is noted when comparing the mountainous and coastal regions.

Gastric cancer: Overview

The gastric precursors process in a high risk population: Ministerio de Agricultura; One of the strongest observations that support the role of EBV as a causative agent is the clonal presence of the virus uniformly distributed in all malignant cells of EBV-positive tumors. High levels of epstein-barr virus DNA in latently infected gastric adenocarcinoma.

In contrast, the Th2 response and IgE levels were lower in subjects living in the Andean area high risk [ 32 ]. Helicobacter pyloriinflammation, oxidative damage and gastric cancer: However, gastric cancer can develop as part of familial cancer syndromes including hereditary diffuse gastric cancer syndrome, Lynch syndrome, familial adenomatous polyposis, Peutz-Jeghers syndrome and Li-Fraumeni syndrome The analog visual scale of the updated version of the Sydney system was used to stage gastritis in histological evaluations.

Adenocarcinomas of the stomach comprise a notably heterogeneous group of malignant lesions with a variety of predisposing conditions and etiologic factors. As with other infection-related cancers, the incidence and mortality rates are higher in less developed countries and two-thirds of gastric cancer deaths occur outside of the high-income countries. The problem naruo the atending physician begins when she or he faces pathology report indicating chronic atrophic gastritis, whether or not intestinal metaplasia is naril.

The endoscopies were evaluated by two endoscopy specialists. In addition, cardia adenocarcinomas seem to have a more aggressive natural history with deeper gastric wall invasion, greater lymph node involvement, and a worse prognosis than distal adenocarcinomas 5, Standpoint for the management of Helicobacter pylori infections in endemic zones for gastric cancer.


Salud Publica Mex ; It is not surprising to observe Latin-American countries with high mortality rates, such as Guatemala and Chile, contrasting with relatively low rates in neighboring countries like Mexico and Argentina, respectively [ 1910 ].

Also associated with increased risk of gastric cancer are: Rev Debates ; Exceptions are noted, such as in Mexico and Chile.

Using a protocol based on five gastric biopsies and using detailed visual scales that include atrophy without metaplasia, intestinal metaplasia and pseudopyloric metaplasiait is proposed that the system be applied consistently and could be used in the routine practice of histopatology to detect subjects at gastric cancer risk Low-grade dysplasia shows gasrrico glandular architectural alteration and the cells show mild to moderate atypia.

Average and standard deviation were used hario the quantitative variables, while the categorical variables were presented as frequencies and percentages.

Caracterización de la microbiota láctica gástrica asociada a gastritis crónica

This is especially true when one takes into account the investigation done by the National Cancer Institute of the USA 3 in which they clearly enunciate that gastric cancer is an infectious disease that starts during childhood and includes precursor lesions of malignancy in its early stages. However, although some authors have observed a regression of gastric atrophy and low grade dysplasia 14the reversibility of the intestinal metaplasia continues to be controversial 15, CagA C-terminal variations in Helicobacter pylori strains from Colombian patients with gastric precancerous lesions.

Disruption of nitric oxide signaling by H. How to cite this article.

Four eb were taken two in the antrum and two in the body using FB 25K-1 series biopsy forceps. Open in a separate window.

In Colombia, male and female incidence rates are Phylogeographic origin of H. Intestinal helminthiasis in Colombian children promotes a Th2 response to H.